Author: Lance Hart

Miniature Brains Grown From Stem Cells

Miniature Brains Grown From Stem Cells

This is an exciting year for developments in stem cell research. So far we’ve seen a miniature but functional human liver, the ‘Google Burger’, and now another mini but major organ. Scientists at the Institute of Molecular Biotechnology at the Austrian Academy of Sciences have reproduced the early stages of brain matter.

Using embryonic and adult skin cells, the neuroscientists have grown a neuroectoderm – the embryonic matter that develops to become the brain and spinal cord. The cells were initially placed in a culture dish and then a gel support structure, before finally being placed inside a spinning bioreactor that “constantly agitates the medium and agitates the organoids inside to allow for better nutrient and oxygen exchange.”

The cells arranged themselves into separate brain regions, such as the cerebral cortex, the retina and even an early hippocampus, the area of the brain responsible for memory function. These brain samples, complete with active neurons, were authentic for nine weeks before the developmental path diverted from that of a regular human brain.

In testing, some brain organoids continued to grow for up to a year, but never exceeding the four millimetres reached at nine weeks.
Without the support of a true circulatory system, complete with blood vessels and rich in nutrients and oxygen, the growth process of the “mini brains” is halted. One of the researchers, Dr Juergen Knoblich of the Institute of Molecular Biotechnology in Vienna, said: “What our organoids are good for is to model development of the brain and to study anything that causes a defect in development.

You may read: Living Healthy While Travelling.

Ultimately we would like to move towards more common disorders like schizophrenia or autism. They typically manifest themselves only in adults, but it has been shown that the underlying defects occur during the development of the brain.”Previously,
human stem cells have been harvested into layers of tissue resembling the brain’s cortex, but this is undoubtedly the next major development in human stem cell research.

The study opens the forum for neurological disorder research using stem cells. Indeed, the researchers used this study to replicate facets of the neurodevelopmental disorder Microcephaly, which causes cognitive impairment and stunted brain growth in humans. The findings mostly confirmed current theories about the disorder, with stem cells taken from a person with Microcephaly lagging behind those collected from a person not afflicted, in growth terms.

At this point there are no concerns over ethics, as the brains are still far off consciousness or awareness, but obviously this will have to be monitored with any future advancement. Because of this, however, the potential to study diseases other than developmental is not yet clear, and neither is the possibility of drug-testing. Brain-affecting drugs and mental health disorder treatment, for instance, are often based on factors including mood, pain and perception, so without the presence of conscious thought, it will not be possible to use this research model for such investigations. Dr Martin Coath, from Plymouth University’s Cognition Institute said “Any technique that gives us ‘something like a brain’ that we can modify, work on, and watch as it develops, just has to be exciting.” If progress in stem cell research continues at this rate, these types of studies could soon become reality.

Living Healthy While Travelling

Living Healthy While Travelling

Living a health life while traveling is not very easy. Before applying for your travel visa with ESTA, you should give a serious thought to a number of important considerations that will help you live a health life for your entire trip.

Below are important things that will help you achieve this noble objective.

Drink many glasses of water

Many people are conscious about the amount of water which they take while at home and this level of consciousness may be ignored when traveling. If you are going to a place where safe water can be found, you should take your bottled water and refill it when necessary. But if you really are in doubt about the quality of water that you could get, you should consider buying bottled water and carrying it with you. There may be some hassle in spending some extra dollars on water and carrying it around may drain your effort, but it’s worth all the work. You will be feeling much better when you are hydrated throughout the day.

Take enough rest

Many people hate jet lag and to get over the very first hump of it, you will need to get enough rest. This is even better is it’s your first day in town. There will be an urge for you to party until sunrise just to announce to the town about your arrival. If you get a full night’s rest, you stand better chances of staying alert and golden the next day. When in a rest mood, you should know that coffee helps a lot, so take enough cups of the drink. The more the rest which you have at the beginning of your trip, the better off you will remain for the entire part of your trip.

Read Also: Recent Findings with Low Testosterone Level.

Engage in some exercise

This is one of the toughest things for someone who is traveling, but if you are used to engaging in regular exercise, your body may experience some withdrawal signs when you are away. A quick jogging up the street can be of great help in this scenario. Most hotels have workout programs and you may space half an hour or so and you will for sure keep your body moving. If it happens that you are on a long flight, you may need to take several laps around the place so as to stretch your legs. With regular exercise, you will find it amazingly easier getting back into groove of things.

Food You Prefer

Take note of the ingredients of the food you eat, how it has been cooked and many more. Don’t just eat anyhow because you are on vacation. You need to ensure that you eat when you are hungry.

Take proper care of your skin

When away from home,you may forget applying your sunscreen whenever required. It’s important that you put on a lotion anytime your face gets dry. It is very important to keep your skin hydrated all the time. Take with you a lotion and face wash which you will use for your entire trip.

Recent Findings with Low Testosterone Level

Recent Findings with Low Testosterone Level

It has been found that obesity is the main reason behind low testosterone levels also known as hypogonadism. Hypogonadism is found in nearly 75% of men considered as obese. This connection is found to be in men of all ages including the teenagers and the young men. It is a myth that low testosterone in older men is due to age. The truth is it is because of increased body weight.

The key findings of the risks associated with low testosterone:

  • Testosterone plays a key role not only in obesity but also for blood glucose control as well as the sensitivity of the body to insulin and the processing of body fats such as triglycerides and cholesterol.
  • The visceral fat increases as men gets older and who have low levels of testosterone.
  • This fat is unhealthy and often linked to diabetes, high blood pressure, heart disease and insulin resistance.
  • There is a strong link between low testosterone in the blood and increased insulin resistance
  • Low testosterone level increases the risk of cardiovascular diseases and type 2 diabetes
  • Decreased level of testosterone is also related to the risk of heart failure.

People with hypogonadism suffer from arterial stiffness and there is a correlation between the total testosterone level and the elastic
properties of the aorta. Arterial stiffness contributes to the cardiovascular conditions that ultimately heighten the risk of mortality. Hypogonadism is also linked with frailty. It has been observed that men with lower levels of testosterone are more likely to be frail when compared with men who have a higher level of testosterone.

Read More: Simple Tips To Lighten Dark Lips Naturally.

Testosterone replacement therapy (TRT) reverses the unfavourable risk associated with hypogonadism.

  • TRT improves lung capacity, exercise tolerance and muscle strength in patient who suffers from chronic heart failure.
  • It has a positive impact on insulin sensitivity specifically in the muscle therefore, leading to an improved flow of blood and oxygen to exercising muscle. This reduces the chances of fatigue.
  • TRT eliminates the risk associated with cardiovascular factors such as metabolic diseases, diabetes and obesity.
  • TRT aid testosterone-deficient elderly men who have limited mobility and cardiovascular diseases. It improves lean body muscles and minimizes the proportion of fat mass in the composition process of the body.
  • TRT increases the metabolism and physical functioning of the body and also increases the strength of the body.
  • It improves the cholesterol or blood lipid profile and improve the sensitivity of the body to insulin.
  • Men with heart disease can benefit from TRT as it improves the exercise capacity, insulin resistance and body composition.

A new finding with low testosterone:

New evidences suggest that hypogonadism can be treated with a new hormone called kisspeptin or named after chocolate. The hormone is made by the human body. It was found in the city of Hershey, Pennsylvania that is famous for chocolates and therefore the hormone is named after the Hershey’s chocolate kiss. During the study, the researchers gave kisspeptin to men with hypogonadism and type 2 diabetes over a 12 hour period using drip.It was found that when kisspeptin was directed, the level of testosterone did not increase above its typical range.Low testosterone can rise abnormally by using supplementary injections
and gels.

Simple Tips To Lighten Dark Lips Naturally

Simple Tips To Lighten Dark Lips Naturally

The problem of dark lips is very common for men or women who are addicted to smoking. However, with some effective skin care remedies, we can manage to get back our lip’s original charm. Healthy lips should glow without any kind of lip balm on it. Factors like smoking, drinking too many teas or coffees in a day or excessive exposure to sun rays can lead to hyper-pigmentation. Excessive production of melanin is known as hyper-pigmentation. Lack of proper lip care or dehydration can turn your lips black.

No worries, if your lips have turned black, we can help them lighten with the following remedies:

Message Your Lips With Essential Oils

Essential oils are like evergreen solutions. The skin absorbs the oils very easily. Among many other essential oils, olive oil is considered the best because of its medicinal properties. When you massage the lips with the essential oils, the blood circulation improves and gives a healthy flush.

Maintaining natural Hydration is Important

If you can keep your lips hydrated most of the times, do that. To maintain the natural moisture balance, drink water throughout the day. You can have different variety of watery fruits to maintain hydration. Watermelons, grapes, lemons and oranges are very good, for example. Don’t let your lips get dry. Dryness can make the lips dark.

 Honey Can Bring Back Your Original Lip Color

Apply honey on your lips to soften the skin and make it pink. Honey has beauty elements that can work well to moisture the skin. You could supply your kip skin with natural nutrients. Your skin will become soft and recover from excess dryness.

You may read: Living With Diabetes: A Diabetics Guide.

Coconut Oil for Dry Lips

Yes, this oil is really precious. You can use this oil for different types of skin problems. This is good for balancing the moisture of the lip skin as well. If you can use it as your cooking oil, that’s the best. You can also take a drop of the oil and apply on your lips before going to bed. That way you can get back the lost moisture of the lips and your lips will become rosy pink.

Mango Butter Cure

Mango butter is the extract of the kernels of the Mango tree. For your knowledge, mango butter is an excellent source of fatty acids. Because the mango butter has stearic acid in it, it can help to moisturize the dryness of the lips. So, if you can manage to apply it for quite a long time, you’ll see a noticeable improvement in your lip condition.

You’ve to Stop Licking Your Lips

That’s not the way to reduce lip dryness. What you can do is put moisturizing balm on your lips instead. That way you can take care of your lips in a better way. When you lick your lips, the saliva wets the lips temporarily. But the saliva dries out easily after some time and takes the natural lip moisture along with it.

Good Foods

There is no way you can have good lips without having good food. Like other skin cells of the body, the skin cells of your lips also need vitamins and minerals to be healthy. You need to take care of your diet to get healthy lips. Foods can give you the essential nutrient necessary for skin cell growth. You need to add a variety of green vegetables and fruit juices to your diet to enjoy the benefits of essential nutrients. If hyper-pigmentation is your problem, then take a lot of vitamin C to get rid of the condition.

Exfoliation

Exfoliate your lips from time to time. It’s important for getting rid of the dead cells. You can use an antibacterial scrub to exfoliate your skin. You can make a natural scrub for lips at home. Make a mixture of lemon juice and sugar and scrub your lips gently with the mixture. Lemon juice is good for lip lightening as its properties act like bleach. The sugar will keep the lips polished. So you’ll get a pair of glowing pinking lips after the exfoliation.  Repeat the process at least once in a week.

Some people have seen good results massaging their lips with ice cubes. It can keep the skin of your lips smooth and glowing.

Living With Diabetes: A Diabetics Guide

Living With Diabetes: A Diabetics Guide

Diabetes is an illness that affects the glucose levels in your blood. It is one of the most common chronic illnesses in the world and the number of people estimated to have either Type 1 or Type 2 diabetes has increased over the years. It can be scary for those who are diagnosed, but there are ways to live a long and healthy life with diabetes.

Develop a diet and regulation plan

Talk to your doctor about a diet and regulation plan. A plan will be part of your treatment, and a healthy diet is essential for managing blood sugar and a healthy weight. Aim to eat plenty of fresh fruit and vegetables and avoid starchy foods like potatoes. The best veggies to include in your meal are carrots, asparagus and leafy greens as they’re low in calories and carbs but full of fibre. Essentially your diet will include; fiber, healthy carbs (fruits, veggies, whole grains), protein (chicken and fish) and finally good fats (avocados, nuts). You’ll need to avoid cholesterol (full fat dairy), saturated fats (deli meats), trans fats (processed foods), and sodium should be consumed in small quantities.

Avoid white foods

That is, white flour, pasta, bread, rice and potatoes. These contain carbohydrates but not enough fiber and protein to help break them down.

Keep moving

Getting exercise will help your body control its glucose levels. Physical activity will make your muscles and fat cells more receptive to insulin. Try to undertake at least 30 minutes of aerobic activity (walking, dancing and running) combined with resistance training (lifting) about three times per week and stretching. When you’re developing your exercise plan, think about the activities you enjoy doing and how you can fit them into your daily schedule.

Consider medication

Not every diabetic will need medication, but as Type 2 diabetes is a progressive disease you may need to increase or change the
medications you are taking. There are six main types of diabetes pills, insulins and a few injectable drugs that lower your blood
glucose. Ask your pharmacists or certified health care professional for details on when and how to take your medication. You’ll have to be regularly monitored by your doctor if you are taking pills, to ensure everything remains stabilised.

Get your blood pressure and cholesterol checked

In addition to checking your glucose levels regularly you should also get your pressure and cholesterol checked. Diabetes doubles your risk of heart disease or stroke and high blood pressure and cholesterol contribute to both. Generally, 130/80 is good for blood pressure. It’s important to keep your cholesterol levels within healthy limits. A normal cholesterol level should be 200 mg or less.

Check your feet daily

Diabetes can lead to poor circulation and loss of sensation in your feet. You’re likely to develop ulcers and calluses on your feet which, if left untreated could lead to an infection. Avoid synthetic materials, especially tight or unventilated shoes and opt for more natural materials such as cotton or leather.